Lecture 6 - Absorption of Toxicants
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Delivery Date
Learning Objectives
- Describe the ways in which toxicants interact with
cells.
- Recognize how the molecular characteristics of toxicants
affect entrance into a cell.
- Explain human anatomy as related to integumentary,
respiratory, and digestive systems.
- Summarize routes of toxicant absorption.
Advance Reading
- Richards, pp 115-128
- NLM Toxicology Tutor
Absorption
- Case Study:
Aldicarb in Watermelons
Resources
Keywords
- Absorption
- Active transport
- Adenosine triphosphate (atp)
- Alveolar region
- Cell membrane
- Concentration gradient
- Digestive system
- Endocytosis
- Epithelial cells
- Epithelium
- Exocytosis
- Facilitated diffusion
- Hydrophilic
- Hydrophobic
- Integumentary system
- Lipid soluble
- Lipophilic
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- Minute volume respiration (mvr)
- Mucociliary escalator
- Nasopharyngeal region
- Nonpolar
- Occluding cell junctions
- Overton’s rules
- Partition coefficient
- Percutaneous
- Phagocytosis
- Phospholipid
- Phospholipid bilayer
- Pinocytosis
- Pneumocytes
- Poiseuille’s Law
- Polar molecules
- Repiratory system
- Semipermeable membrane
- Simple diffusion
- Tracheobronchial region
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Suggested Reading
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Slides
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