Lecture 7 - Distribution and Storage of Toxicants

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Learning Objectives

1. Identify the way toxicants are distributed by the body.
2. Recognize the relationship between a specific route of absorption and the related pathways for distribution of a toxicant.
3. Describe the factors affecting distribution of toxicants to tissues.
4. Define volume of distribution.
5. List the sites for toxicant storage.
6. Discuss how storage influences toxicant half-life.
7. Perform an LD50 experiment.

Advance Reading:

1. Richards, pp 129-132
2. NLM Toxicology Tutor Distribution

Resources

Keywords

Suggested Reading

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