Learning Objectives

1. Examine the etiology (causation) of human disease related to naturally-occurring foodborne toxicants.
2. Understand the chemical complexity of foods.
3. Explore goiter, tropical ataxia neuropathy (TAN), tropical amblyopia, lathyrism, and their linkage to foodborne toxicants.
4. Review a range of natural food toxicants that are involved in human disease.

Advance Reading

• Shibamoto, pp. 67-83

Suggested Reading

1. What is G6PD Deficiency? G-6-PD Deficiency Association
2. Plant Toxins: Lathyrism
3. Plant Toxins: Konzo
4. Acetylcholine and Synaptic Receptors
5. Plant Toxins: Ricin
6. Plant Toxins: Veno-occlusive Disease
7. Plant Toxins: Cardiac Glycosides

Keywords

1. Goiter
2. Tropical ataxia neuropathy (TAN)
3. Tropical amblyopia
4. Lathyrism
5. Goitrogens
6. Cyanogenic glycosides
7. Lectins
8. Alkaloids
9. Protease inhibitors
10. Vasoactive amines

11. Osteolathyrism
12. Neurolathyrism
13. Beta-L-glutamylaminoproprionitrile
14. B-N-oxalyl-L-alpha,B-diaminoproprionic acid